Studies on Pyridazinone Derivatives. IV : Synthesis and Antibacterial Antifungal Activity of Sulfur-containing Pyridazinone Derivatives
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چکیده
منابع مشابه
Synthesis and Anticonvulsant Activity of Pyridazinone Derivatives
In the recent years there has been an increased interest in the pyridazinone ring system. Many investigations indicated that the presence of at least one aryl group, one or two electron donor atoms and/or an NH group in a special spatial arrangement is necessary for anticonvulsant activity. Many investigations indicated that the presence of at least one aryl group, one or two electron donor ato...
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A series of pyridazinone derivatives (19-34) were synthesized with an aim to synthesize safer anti-inflammatory agents. The compounds were evaluated for their anti-inflammatory, analgesic, ulcerogenic and lipid peroxidation (LPO) actions. The percentage inhibition in edema at different time intervals indicated that compounds 20, 26, 28 and 34 exhibited good anti-inflammatory potential, comparab...
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New 3(2H)-pyridazinone derivatives containing a N'-benzyliden-acetohydrazide moiety at position 2 were synthesized. The structures of these newly synthesized compounds were confirmed by IR, 1H NMR, and MS data. These compounds were tested for their antibacterial, antifungal, antimycobacterial, and cytotoxic activities. The compounds 2-[4-(4-chlorophenyl)-6-(morpholin-4-yl)-3-oxo-(2H)-pyridazin-...
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ژورنال
عنوان ژورنال: YAKUGAKU ZASSHI
سال: 1969
ISSN: 0031-6903,1347-5231
DOI: 10.1248/yakushi1947.89.11_1516